PUF60 anticorps (AA 346-533)
Aperçu rapide pour PUF60 anticorps (AA 346-533) (ABIN1886388)
Antigène
Voir toutes PUF60 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 346-533
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 533 of Human PUF60
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
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Autre désignation
- PUF60
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Sujet
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The protein encoded by this gene is a Ro RNP-binding protein.It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs.This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein.It can repress a c-myc reporter via the FUSE.It is also known to target transcription factor IIH and inhibit activated transcription.This gene is implicated in the xeroderma pigmentosum disorder.There are two alternatively spliced transcript variants of this gene encoding different isoforms.There seems to be evidence of multiple polyadenylation sites for this gene.[provided by RefSeq]
Synonyms: FIR, PUF60, RoBPI -
Poids moléculaire
- 58 kDa
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ID gène
- 22827
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NCBI Accession
- NP_055096, NM_014281
Antigène
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